Research Technician
Kennziffer: 2024-0331
- Heidelberg
- Vollzeit
- Junior Research Group "Epithelium Microbiome Interactions"
„Forschen für ein Leben ohne Krebs“ – das ist unsere Aufgabe am Deutschen Krebsforschungszentrum. Wir erforschen, wie Krebs entsteht, erfassen Krebsrisikofaktoren und suchen nach neuen Strategien, die verhindern, dass Menschen an Krebs erkranken. Wir entwickeln neue Methoden, mit denen Tumore präziser diagnostiziert und Krebspatient:innen erfolgreicher behandelt werden können. Jeder Beitrag zählt – ob in der Forschung, in der Administration oder der Infrastruktur. Das macht unsere tägliche Arbeit so bedeutungsvoll und spannend.
Our Junior Research Group "Epithelium Microbiome Interactions" (headed by Dr. Jens Puschhof) is seeking a
Our junior research group studies how bacteria contribute to cancer development, metastasis and treatment response. Our team includes cancer researchers, tissue engineers, microbiologists, and bioinformaticians working together to help patients by deciphering the functional impacts of bacteria in human tumors. In our projects, we use organoid, organ chip and in vivo platforms to dissect the mechanisms of cancer-microbe interactions.
We are looking for a qualified and motivated research technician (BTA, MTA, Biologielaborant or similar) to support in vivo and in vitro experiments on several projects focused on the role of the microbiome in cancer development and progression in our group.
Ihre Aufgaben:
The candidate will be trained in and responsible for the generation and maintenance of next-generation patient-derived in vitro culture models including organoids and isolated bacterial strains. The candidate will furthermore take care of research animals following standard operating procedures and according to animal welfare regulations. Additionally, the candidate will learn and apply a variety of laboratory techniques, such as DNA/RNA isolation and purification, protein extraction, genotyping by PCR, sample preparation for down-stream analyses, and flow cytometry.
Responsibilities will include:
- Generation and maintenance of human tumor organoid lines
- Derivation of patient-specific bacterial strains
- Support of standard laboratory techniques, including DNA/RNA isolation and FACS
- Collecting, handling/processing, and storing of biological samples (e.g. patient feces, blood, tissue) according to standard protocols.
- Regular monitoring of animal health and data recording (such as animal weight, behavior, vital signs, tumor growth).
- Performing basic procedures on animals (including weighing, oral gavaging, injections, dissection).
- Operating sensitive equipment to analyze samples or substances, conducting tests and reporting results.
- Recording and analyzing data
Ihr Profil:
Required:
- Education/training as lab technician or technical assistant (BTA, MTA, Biologielaborant:in) or comparable
- Strong organizational and time management skills
- Reliability and flexibility
- Structured, independent, and careful way of working, e.g. ability to implement a variety of laboratory techniques using standard protocols after a thorough training by our scientific staff members
- Written and oral communication skills (German and English)
Advantageous:
- FELASA function A certificate (former FELASA B certificate)
- Proven working experience with animal models
- Hands-on working experience with cell culture (maintaining cell lines, establishing primary cell cultures) and/or molecular biology techniques (DNA/RNA isolation, PCR) would be an advantage
Unser Angebot:
- Hervorragende Rahmenbedingungen: modernste state-of-the-art Infrastruktur und Möglichkeit zum internationalen Austausch auf Spitzenniveau
- 30 Tage Urlaub
- Flexible Arbeitszeiten
- Vergütung nach TV-L inkl. betrieblicher Altersvorsorge und vermögenswirksamer Leistungen
- Möglichkeit zur Teilzeitarbeit
- Familienfreundliches Arbeitsumfeld
- Nachhaltig zur Arbeit: Vergünstigtes Deutschland-Jobticket
- Entfalten Sie Ihr volles Potenzial: gezielte Angebote für Ihre persönliche Entwicklung fördern Ihre Talente
- Unser betriebliches Gesundheitsmanagement bietet ein ganzheitliches Angebot für Ihr Wohlbefinden
Sie sind interessiert?
Dr. Jens Puschhof
Telefon: +49 6221 42 4953
