Data Scientist in the field of Cancer Genomics / Epigenomics
Kennziffer: 2024-0258
- Heidelberg
- Vollzeit
- Pediatric Neurooncology
„Forschen für ein Leben ohne Krebs“ – das ist unsere Aufgabe am Deutschen Krebsforschungszentrum. Wir erforschen, wie Krebs entsteht, erfassen Krebsrisikofaktoren und suchen nach neuen Strategien, die verhindern, dass Menschen an Krebs erkranken. Wir entwickeln neue Methoden, mit denen Tumore präziser diagnostiziert und Krebspatient:innen erfolgreicher behandelt werden können. Jeder Beitrag zählt – ob in der Forschung, in der Administration oder der Infrastruktur. Das macht unsere tägliche Arbeit so bedeutungsvoll und spannend.
The Division of Pediatric Neurooncology at the German Cancer Research Center and the Hopp Children's Cancer Center Heidelberg is seeking a
The Hopp Children's Cancer Center Heidelberg (KiTZ) is a joint institution of the German Cancer Research Center (DKFZ), the Heidelberg University Hospital (UKHD) and the University of Heidelberg (UniHD). As a treatment and research center for oncological and hematological diseases in children and adolescents, the KiTZ is committed to scientifically explore the biology of childhood cancer and closely link promising research approaches with patient care – from diagnosis to treatment and aftercare.
The Division of Pediatric Neurooncology at the German Cancer Research Center and the Hopp Children's Cancer Center Heidelberg is seeking to fill a data scientist position in computational biology for the DNA methylation classifier project.
The “Clinical Bioinformatics – Translational Genomics” group led by Dr. Robert J. Autry focuses on developing computational methods and workflows to answer clinically relevant questions across the range of childhood cancers by interrogating genomic and epi-genomic alterations. We aim to elucidate the mechanisms underlying cancer predisposition, tumorigenesis and therapeutic response to discover novel therapeutic targets and to improve diagnosis, prevention, risk stratification, disease monitoring and clinical outcome in children.
Ihre Aufgaben:
A postdoctoral / data scientist position is available in our group for a highly motivated and skilled computational biologist. The successful candidate will lead a project aimed at establishing and developing innovative computational approaches to develop and train models (e.g., random forest, neural network) used to maintain and enhance DNA methylation tumor classifiers developed in the Division of Pediatric Neurooncology at the KiTZ / DKFZ in Heidelberg.
This is an exciting opportunity for a computationally minded leader to learn and develop computational tools to improve and automate the established gold standard methylation classifier for tumors. Additionally, this position offers opportunities to initiate novel projects in tumor classification, early detection, and functional characterization, as well as explore potential applications beyond pediatric oncology. The candidate will work with large cancer datasets, engaging in cutting-edge clinical cancer research and collaborating with teams worldwide.
Moreover, this role will involve close interaction with Heidelberg Epignostix GmbH (https://epignostix.com/), a subsidiary company developed from our research initiatives, providing a unique interface between academic research and commercial application. The successful candidate will be uniquely positioned at the interface of bioinformatics, clinical research, and translational innovation, with a dynamic outlook towards both scientific discovery and its real-world application.
For more information about the Autry Group, visit our website.
Ihr Profil:
- PhD and master's degree (or equivalent) in bioinformatics, computational biology, genomics, biostatistics, computer science, or a related field
- 2+ years of postdoctoral experience (recommended but not required)
- Strong bioinformatics analytical skills and experience with Linux / Unix command line and programming languages (e.g., R, Python, Bash)
- Desired experience in database management (SQL) and app development (e.g., Shiny)
- Encouraged experience in machine learning and high-performance computing environments
- Expertise in the analysis and integration of next-generation sequencing and other multi-omics data is a plus
- Excellent communication skills in English with the ability to write publications, present research proposals and results, and represent the lab at meetings and conferences
- Excellent interpersonal skills with the ability to work independently and as part of a team
Unser Angebot:
- Hervorragende Rahmenbedingungen: modernste state-of-the-art Infrastruktur und Möglichkeit zum internationalen Austausch auf Spitzenniveau
- 30 Tage Urlaub
- Flexible Arbeitszeiten
- Vergütung nach TV-L inkl. betrieblicher Altersvorsorge und vermögenswirksamer Leistungen
- Möglichkeit zur mobilen Arbeit und Teilzeitarbeit
- Familienfreundliches Arbeitsumfeld
- Nachhaltig zur Arbeit: Vergünstigtes Deutschland-Jobticket
- Entfalten Sie Ihr volles Potenzial: gezielte Angebote für Ihre persönliche Entwicklung fördern Ihre Talente
- Unser betriebliches Gesundheitsmanagement bietet ein ganzheitliches Angebot für Ihr Wohlbefinden
Sie sind interessiert?
Dr. Robert Autry
Telefon: +49 (0)6221/42-3639
