Position: Postdoc in Bioinformatics - Translational Control and Metabolism

Department: Translational Control and Metabolism

Code number: 2022-0135

The German Cancer Research Center is the largest biomedical research institution in Germany. With more than 3,000 employees, we operate an extensive scientific program in the field of cancer research.

The Loayza-Puch lab (Junior Research Group Translational Control and Metabolism) is interested in uncovering metabolic deficiencies in cancer. We exploit the translation machinery to infer amino acid limitations in tumors. For this purpose, we developed novel sequencing tools to study metabolic interactions in the tumor microenvironment. We’re looking for an enthusiastic and ambitious bioinformatician to join our team.

 

Job description:

The successful candidate will develop and apply computational tools for the analysis of translatome and transcriptome data from experiments designed to understand metabolic interactions in the tumour microenvironment (TME). In addition, the applicant will develop bioinformatic pipelines for the analysis of single-cell ribosome profiling data to characterize amino acid limitations in multiple populations of the TME. Furthermore, the applicant will be in charge of analyzing functional genetic screens designed to dissect regulatory elements important for mRNA translation.

Requirements:

We are looking for a creative and highly motivated bioinformatician who holds a PhD degree in computer science, bioinformatics, or a related field. The successful candidate will have a proven record in the use of Linux / Unix and should be proficient in the analysis of next generation sequencing data (RNA-seq, CRISPR-screens datasets, etc). Proficiency in scripting and software development (e.g., Python, C / C++, Java, R) is desired. The ability to work in an environment at the interface of biology and computer sciences in addition to good communication skills are essential. Experience in the analysis of Ribo-seq datasets and/or single-cell sequencing data is an advantage. We expect the candidate to work independently and to have basic cancer metabolism knowledge.

The application should include a CV, motivation letter, the expected availability date, a complete list of publications, degrees and the names and contact information of at least two references.

We offer:

  • Interesting, versatile workplace
  • International, attractive working environment
  • Campus with modern state-of-the-art infrastructure
  • Salary according to TV-L including social benefits
  • Possibility to work part-time
  • Flexible working hours
  • Comprehensive further training program
  • Access to the DKFZ  International Postdoc Program

Important notice:

The DKFZ is subject to the regulations of the Infection Protection Act (IfSG). As a consequence, only persons who present proof of immunity against measles as well as against COVID-19 may work at the DKFZ.

Earliest possible start date: as soon as possible

Duration: The position is initially limited to 2 years with the possibility of prolongation. ‚Äč

The position can in principle be part-time.

Application deadline: 02.06.2022

Contact:

Dr. Fabricio Loayza-Puch
Phone +49(0)6221/42-3632

Please note that we do not accept applications submitted via email.

The DKFZ is committed to increase the proportion of women in all areas and positions in which women are underrepresented. Qualified female applicants are therefore particularly encouraged to apply.

Among candidates of equal aptitude and qualifications, a person with disabilities will be given preference.

To apply for a position please use our online application portal (https://www.dkfz.de/en/stellenangebote/index.php).

We ask for your understanding that we cannot return application documents that are sent to us by post (Deutsches Krebsforschungszentrum, Personalabteilung, Im Neuenheimer Feld 280, 69120 Heidelberg) and that we do not accept applications submitted via email. We apologize for any inconvenience this may cause.