Position: Research Scientist

Department: Single-cell Open Lab (scOpenLab)

Code number: 2022-0156

The German Cancer Research Center is the largest biomedical research institution in Germany. With more than 3,000 employees, we operate an extensive scientific program in the field of cancer research.

Recent technological advancements make it now possible to combine genome-wide single-cell omics readouts with a microscopy-based analysis to integrate imaging-based phenotypes and molecular profiles in spatially resolved omics (SRO) approaches. A position as a computational scientist to support the analysis of SRO is available at the DKFZ. The work is embedded in a larger initiative for building an SRO technology platform across institutions on the Innovation Campus Heidelberg-Mannheim. 

We are looking for a research scientist to implement, advance and maintain experimental SRO workflows. The successful candidate will be part of an interdisciplinary research team for developing and applying a diverse range of state-of-the-art SRO methodology that comprises the complete workflow from the experimental data generation to clinical applications. The position provides the unique opportunity to build an internationally competitive SRO technology platform.


Job description:

  • Provide training and service for spatial omics technologies
  • Support project and probe design
  • Testing / benchmarking commercial workflows
  • Developing and optimizing new read-outs tailored to research questions addressed by the users
  • Support of data access and analysis workflows across institutions

(Please note that the job description was updated on 6 May 2022.)


  • Master's degree or equivalent qualification in life science with experience in single-cell sequencing and/or imaging technologies of at least 2 years, PhD is an advantage
  • Background in microscopy methods, e.g., single molecule FISH and related in situ hybridization techniques as well as next generation sequencing
  • Proficiency in histology techniques, automated liquid handling and probe design is beneficial
  • Previous experience with single-cell sequencing technologies and imaging data analysis and management is a plus

The ideal applicant should have demonstrated the ability to work independently and creatively. The candidate should have good communications skills in English to articulate the technical needs, set clear milestones for the projects and should be motivated to work within an interdisciplinary team with other bioinformaticians as well as experimentalists.

We offer:

  • Interesting, versatile workplace
  • International, attractive working environment
  • Campus with modern state-of-the-art infrastructure
  • Salary according to TV-L including social benefits
  • Possibility to work part-time
  • Flexible working hours
  • Comprehensive further training program

Important notice:

The DKFZ is subject to the regulations of the Infection Protection Act (IfSG). As a consequence, only persons who present proof of immunity against measles as well as against COVID-19 may work at the DKFZ.

Earliest Possible Start Date: as soon as possible

Duration: The position is initially limited to 2 years. An extension up to 5 years would be possible.

The position can in principle be part-time.

Application Deadline: 26.05.2022


Dr. Jan-Philipp Mallm
Phone +49 (0)6221/54-51378

Please note that we do not accept applications submitted via email.

The DKFZ is committed to increase the proportion of women in all areas and positions in which women are underrepresented. Qualified female applicants are therefore particularly encouraged to apply.

Among candidates of equal aptitude and qualifications, a person with disabilities will be given preference.

To apply for a position please use our online application portal (https://www.dkfz.de/en/stellenangebote/index.php).

We ask for your understanding that we cannot return application documents that are sent to us by post (Deutsches Krebsforschungszentrum, Personalabteilung, Im Neuenheimer Feld 280, 69120 Heidelberg) and that we do not accept applications submitted via email. We apologize for any inconvenience this may cause.