Job description:

The postdoc will be working on dissecting the roles of different targets in metastatic bone colonization and interactions at the interface between tumor and host with a focus on the endosteal niche. Furthermore, they will be deciphering this crosstalk in the context of anti-tumor immune responses. The project comprises state-of-the-art preclinical models of specific treatments against characterized targets together with anti-cancer immune therapies. In addition, primary cell cultures, genetic knockdown expression and innovative single-cell technologies will be performed.

We are offering an interesting and challenging field of work as well as an excellent work environment in a dynamic and multinational team, which works closely with national as well as international collaboration partners in academics as well as pharmaceutical companies. The location is Heidelberg.

Requirements:

We are looking forward to receive applications from highly motivated scientists. Applicants should hold a master's degree in biology or a related field as well as a PhD in this scientific area, with a track record of publications in peer-reviewed journals. Applicants should ideally have a documented strong expertise in bone morphology and cancer biology, cell culture, as well as animal application writing and in vivo (mouse) experience including FELASA B or C certificate. Knowledge in molecular biology techniques such as isolation of nucleic acids (RNA, DNA), cDNA synthesis, Western Blot, qRT-PCR and CRISPR/Cas9 are positively valued.

The scientist on this position is expected to work independently but collaboratively with other lab members as well as with other research groups. An excellent communication skill for scientific discussion is indispensable and proficiency in English is mandatory.

Full applications should include curriculum vitae, a letter of motivation, certificates, expected availability date, a list of publications and 2-3 references.