Position: PhD Student – Hyperpolarized Metabolic Imaging
Department: DKTK Tübingen - Department of Preclinical Imaging and Radiopharmacy, University Hospital Tübingen (UKT)
Code number: 2022-0421
The German Cancer Research Center is the largest biomedical research institution in Germany. With more than 3,000 employees, we operate an extensive scientific program in the field of cancer research.
Together with university partners at seven renowned partner sites, we have established the German Cancer Consortium (DKTK).
The DKTK partner site Tübingen is seeking for the Werner Siemens Imaging Center (Department of Preclinical Imaging and Radiopharmacy) at the University Hospital Tübingen (UKT) applications from highly motivated candidates for a PhD position in multiplex preclinical hyperpolarized metabolic imaging.
This position is part of the DKTK-funded project „HYPERBOLIC - Visualizing Hallmarks of Cancer through tailored Hyperpolarized Magnetic Resonance Imaging.” The main task of the position is the implementation of relevant preclinical disease models and the application of innovative molecular imaging agents for visualization of, e.g., pH, hypoxia, metabolism, and oxidative stress for image-guided therapies with hyperpolarized MRS and hybrid PET/MR imaging.
The PhD position is embedded within the AMICI lab “Advanced Metabolic Imaging and Cell Engineering” led by Prof. Dr. André F. Martins (isct: Advanced Preclinical Metabolic Imaging and Cell Engineering (uni-tuebingen.de)). The Werner Siemens Imaging Center (Department of Preclinical Imaging and Radiopharmacy) is a world-leading imaging center recognized for its scientific excellence and unique state-of-the-art imaging. The development of novel diagnostics and therapeutic approaches for the treatment of tumor diseases is one of the main objectives of the department and its collaborators (iFIT Cluster of Excellence). Together with the University Hospital of Tübingen (UKT) and the Max Planck Institutes, we will develop techniques to image the tumor microenvironment, guide therapy through multimodal imaging, and perform functional quantitative imaging.
We offer to work on a high scientific level in an experienced and well-funded research team with an excellent interdisciplinary infrastructure providing a state-of-the-art life science and clinical environment. With this position, the candidate will have the opportunity to publish in leading international journals and present the research to an international scientific community. Furthermore, we are connected to a strong network providing an excellent platform to cooperate with local, national, and international research labs.
We are looking for an enthusiastic and highly motivated PhD student eager to work in an interdisciplinary environment. The successful candidate should share our ambition that optimized molecular hyperpolarized imaging can address significant biological questions in cancer metabolism at the preclinical and clinical levels. Applicants should hold a university degree in molecular medicine, biomedical imaging, (bio-) chemistry, medicinal, and pharmaceutical sciences, or related fields. Lab-routine skills are mandatory - ideally, but not necessary, with specific experience in hyperpolarized MR tracers for preclinical imaging. The successful candidate will be expected to have at least one of the following skills: in vivo animal imaging and/or wet-lab biochemistry skills. Excellent communication skills in English are required.
- Interesting, versatile workplace
- International, attractive working environment
- Campus with modern state-of-the-art infrastructure
- Access to international research networks
- Doctoral student payment including social benefits
- Flexible working hours
- Comprehensive training and mentoring program through the Helmholtz International Graduate School
The DKFZ is subject to the regulations of the Infection Protection Act (IfSG). As a consequence, only persons who present proof of immunity against measles as well as against COVID-19 may work at the DKFZ.
Earliest Possible Start Date: 02.01.2023
Duration: The position is limited to 3 years with the possibility of prolongation.
Application Deadline: 02.12.2022
Prof. Dr. André Martins
Phone 07071 29 87487
Please note that we do not accept applications submitted via email.