Position: Postdoctoral Researcher

Department: Mechanisms Regulating Gene Expression

Code number: 2024-0107

The German Cancer Research Center is the largest biomedical research institution in Germany. With more than 3,000 employees, we operate an extensive scientific program in the field of cancer research.

We are currently looking for a postdoctoral researcher to join the group of Prof. Dr. Michaela Frye (Division of Mechanisms Regulating Gene Expression) in Heidelberg.


Job description:

The Frye lab studies the function of RNA modifications in cancer development, metastasis and therapy resistance. You will be part of an exciting and stimulating research environment, working closely with a team of researchers, clinicians and computational analysts. Our project addresses the question how RNA modifications dynamically control transcription and mRNA translation when cancer cells are exposed to a new environment during metastasis or cancer treatment regimens for example.

We utilize a wide array of biochemical, cellular, computational and in vivo approaches to identify novel epitranscriptomic key players. A major part will be the integration of nanopore sequencing approaches for full-length transcript analyses and base modification detection.



Candidates must have a PhD or equivalent degree and at least one first author publication. We are looking for highly motivated candidates with a strong background in molecular/cellular biology, stem cell biology, and transgenic mouse models, but even more important is their motivation to learn and adapt to scientific challenges and become a positive member of the lab.The position requires proficiency in spoken and written English.

Starting date is flexible but can be as early as June 2024.

We offer:

  • Interesting, versatile workplace
  • Excellent framework conditions: state-of-the-art equipment and opportunity for international networking at the highest level
  • Remuneration according to TV-L incl. occupational pension plan for the public service and capital-forming payments
  • 30 days of vacation per year
  • Flexible working hours
  • Possibility of mobile work and part-time work
  • Family-friendly working environment, including parent-child room, counseling services, e.g. on Elder Care
  • Sustainable travel to work: subsidized Germany job ticket
  • Develop your full potential: access to the DKFZ International Postdoc Program and DKFZ Career Service with targeted offers for your personal development to further develop your talents
  • Our Corporate Health Management Program offers a holistic approach to your well-being

Important notice:

The DKFZ is subject to the regulations of the Infection Protection Act (IfSG). As a consequence, only persons who present proof of immunity against measles may work at the DKFZ.

Earliest possible start date: 01.06.2024

Duration: The position is initially limited to 1 year. ‚Äč

Application deadline: 17.04.2024


Prof. Dr. Michaela Frye
Phone +49 6221/42-4165

Please note that we do not accept applications submitted via email.

The DKFZ is committed to increase the proportion of women in all areas and positions in which women are underrepresented. Qualified female applicants are therefore particularly encouraged to apply.

Among candidates of equal aptitude and qualifications, a person with disabilities will be given preference.

To apply for a position please use our online application portal (https://www.dkfz.de/en/stellenangebote/index.php).

We ask for your understanding that we cannot return application documents that are sent to us by post (Deutsches Krebsforschungszentrum, Personalabteilung, Im Neuenheimer Feld 280, 69120 Heidelberg) and that we do not accept applications submitted via email. We apologize for any inconvenience this may cause.