Technical Assistant for mRNA Cancer Immunotherapies

Reference number: 2024-0197

  • Mainz
  • Full-time
  • HI-TRON Mainz - mRNA Cancer Immunotherapies

“Research for a life without cancer" is our mission at the German Cancer Research Center. We investigate how cancer develops, identify cancer risk factors and look for new cancer prevention strategies. We develop new methods with which tumors can be diagnosed more precisely and cancer patients can be treated more successfully. Every contribution counts – whether in research, administration or infrastructure. This is what makes our daily work so meaningful and exciting.

The Helmholtz Institute HI-TRON in Mainz is a collaboration of the German Cancer Research Center (DKFZ) with the Johannes Gutenberg-University (JGU), the University Medicine Mainz (UM Mainz) and the non-profit TRON gGmbH (TRON). The aim of the partnership is to develop pioneering immunotherapies and identify new biomarkers for the effectiveness of the treatment.

The Division "mRNA Cancer Immunotherapies" at HI-TRON headed by Prof. Dr. Uğur Şahin focuses on the identification of biomarkers or targets for immunotherapy and the development of novel mRNA-assisted therapeutic strategies.

To strengthen our international scientific team, we are looking for a highly motivated and enthusiastic


Your Tasks

  • Cell biology techniques including processing of human blood and tissue samples, primary cell culture (especially of immune cells) as well as culture of 2D and 3D cell models, and co-cultures of tumor and immune cells
  • Immunological assays including ELISA, FACS, ELISpot, IHC/IF staining
  • Molecular biology methods such as single-cell sequencing, DNA/RNA isolation, PCR, library preparation, cloning, in vitro transcription
  • Support with animal experiments
  • General laboratory organization, administration and management
  • In areas of core competency, you will also be responsible for the creation of protocols and work instructions, and training of colleagues
  • Active participation in lab discussions and data analysis 

Your Profile

  • Successfully completed training as a technical assistant (BTA, CTA, MTA), biology laboratory assistant or comparable qualification
  • Willingness to work with blood and tissue samples
  • Experience in molecular biology and cell culture
  • Prior knowledge of immunological methods is an advantage
  • Willingness to work with animals (at least FELASA A is recommended)
  • High degree of initiative, independence and organizational skills
  • Ability to work in a team and interest in scientific work, sense of responsibility, accuracy
  • Good communication skills in English
  • Knowledge of MS Office

We Offer

  30 days of vacation per year

  Flexible working hours

  Remuneration according to TV-L incl. occupational pension plan and capital-forming payments

  Possibility of part-time work

  Family-friendly working environment

  Sustainable travel to work: subsidized Germany job ticket

  Unleash your full potential: targeted offers for your personal development to further develop your talents

  Our Corporate Health Management Program offers a holistic approach to your well-being

  Excellent framework conditions: state-of-the-art equipment and opportunities for international networking at the highest level

Are you interested?

Then become part of the DKFZ and join us in contributing to a life without cancer!


Dr. Alexandra Alves Duarte
Telefon: +49 (0)6131/17-9768

Duration: The position is initially limited to 2 years with the possibility of prolongation.
Application Deadline: 26.07.2024
Applications by e-mail cannot be accepted.

We are convinced that an innovative research and working environment thrives on the diversity of its employees. Therefore, we welcome applications from talented people, regardless of gender, cultural background, nationality, ethnicity, sexual identity, physical ability, religion and age. People with severe disabilities are given preference if they have the same aptitude.

Notice: We are subject to the regulations of the Infection Protection Act (IfSG). Therefore, all our employees must provide proof of immunity against measles.

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