Position: Postdoctoral Fellow in Computational Biology

Department: Somatic Evolution and Early Detection

Code number: 2019-0196

The German Cancer Research Center is the largest biomedical research institution in Germany. With approximately 3,000 employees, we operate an extensive scientific program in the field of cancer research.

The Goncalves and Odom laboratories have a shared interest in understanding the mechanisms of somatic genome and regulatory evolution during ageing and carcinogenesis. We are developing multiple projects that combine single-cell sequencing, functional analysis, and comparative genomics with an eventual goal of understanding how perturbation of genetic sequences can lead to human tumours.

Job description:

A successful candidate will be shared between the laboratories and have substantial latitude in designing their research project in close discussions with Drs Goncalves and Odom. Currently available research projects include: investigating the mechanisms underlying ageing associated increases in cell-to-cell transcriptional variability, the comparative functional genomics of mammalian somatogenesis, comparative genomics of somatic mosaicism, and how CTCF lends stability to vertebrate genomes during ageing.

Projects will involve close collaboration with experimental postdocs in the Odom laboratory, as well as other collaborative partners. The post holder will be responsible for project management, computational method development and optimisation, and analysis of novel and large genomic datasets. This post is supported by core-funding from the Helmholtz Society.

For more information on Goncalves and Odom research, please see:
https://goncalves-lab.github.io
https://scholar.google.de/citations?user=4dTaKOQAAAAJ&hl=en
https://scholar.google.co.uk/citations?hl=en&user=I4QxyoQAAAAJ

Requirements:

We are seeking a postdoctoral research fellow with extensive computational biology expertise to join our efforts. An ideal candidate is collaborative, ambitious, meticulous, scientifically adventurous, and curiosity-driven. Prior bioinformatics training in analysis of single-cell transcription, transcriptional regulation, epigenetics, evolutionary biology, and/or comparative genomics would be advantageous.

We offer:

  • Interesting, versatile workplace
  • International, attractive working environment
  • Campus with modern state-of-the-art infrastructure
  • Salary according to TV-L including social benefits
  • Possibility to work part-time
  • Flexible working hours
  • Comprehensive further training program
  • Access to the DKFZ  International Postdoc Program

Earliest possible start date: zum nächstmöglichen Zeitpunkt

Duration: The position is limited to 2 years with the possibility of prolongation.

The position can in principle be part-time.

Application deadline: 03.07.2019

Contact:

Dr. Angela Teresa Filimon Goncalves
Phone +49(0)6221/42-1280

Please note that we do not accept applications submitted via email.


The German Cancer Research Center is committed to increase the percentage of female scientists and encourages female applicants to apply. Among candidates of equal aptitude and qualifications, a person with disabilities will be given preference.                           

To apply for a position please use our online application portal (www.dkfz.de/jobs).

We ask for your understanding that we cannot return application documents that are sent to us by post (Deutsches Krebsforschungszentrum, Personalabteilung, Im Neuenheimer Feld 280, 69120 Heidelberg) and that we do not accept applications submitted via email. We apologize for any inconvenience this may cause.