Position: Postdoctoral Fellow in Cancer Genetics & Molecular Biology

Department: DKTK Freiburg - Department of Thoracic Surgery

Code number: 2020-0046

The German Cancer Research Center is the largest biomedical research institution in Germany. With approximately 3,000 employees, we operate an extensive scientific program in the field of cancer research.

Together with university partners at seven renowned partner sites, we have established the German Cancer Consortium (DKTK). For the partner site of DKTK Freiburg the German Cancer Research Center is seeking a postdoctoral fellow.

Our research division explores the molecular mechanisms underlying carcinogenesis with a special emphasis on non-canonical and novel types of mutations in cancer (EMBO Mol Med 2016, Nat Commun 2019, Nat Cell Biol - in 2nd revision). The method spectrum in our lab ranges from innovative techniques from molecular and cell biology like diverse CRISPR techniques (Nucleic Acids Res 2017, Hepatology 2018) or RNA-Protein complex identification (Nature 2015, Mol Cell 2019, Nat Protoc 2020) to applications in bioinformatics and biochemistry. Our lab in Freiburg is newly equipped with state-of-the-art instrumentation.

Job description:

We are seeking a highly motivated, ambitious postdoctoral fellow with significant and published experience in the area of molecular biology and / or cancer research, ideally in cancer genetics. The core project of the postdoctoral fellow will be the functional characterization of non-canonical genetic alterations in cancer in higher through-put. Research questions will include their impact at the cellular and molecular level on mRNA and protein expression and their mechanistic impact. An innovative screen using CRISPR site-directed mutagenesis shall unravel their impact on human cells. Comprehensive resources as well as established protocols to build on are available. Jointly with the division head, new projects within the focus area of the lab can also be developed and supported to allow the growth into scientific maturity and independence.


You are a highly motivated postdoctoral fellow with a PhD / Dr. rer. nat. in a life science field and are eager to pursue and lead research projects in tumor genetics and the molecular biology of cancer including high through-put approaches and genome editing with ambition, creativity, independence and team spirit. You have published experience in techniques of cellular and molecular biology or cancer research. Practical knowledge of bioinformatics would be welcome. You work efficiently, goal-oriented and accurate, have a deep interest in research and are proficient in English.

We offer:

  • Interesting, versatile workplace
  • International, attractive working environment
  • Campus with modern state-of-the-art infrastructure
  • Salary according to TV-L including social benefits
  • Possibility to work part-time
  • Flexible working hours
  • Comprehensive further training program
  • Access to the DKFZ  International Postdoc Program

Earliest possible start date: as soon as possible

Duration: The position is limited to 2 years.

The position can in principle be part-time.

Application deadline: 27.02.2020


Prof. Dr. Sven Diederichs
Phone +49(0)761 270-77571

Please note that we do not accept applications submitted via email.

The German Cancer Research Center is committed to increase the percentage of female scientists and encourages female applicants to apply. Among candidates of equal aptitude and qualifications, a person with disabilities will be given preference.                           

To apply for a position please use our online application portal (www.dkfz.de/jobs).

We ask for your understanding that we cannot return application documents that are sent to us by post (Deutsches Krebsforschungszentrum, Personalabteilung, Im Neuenheimer Feld 280, 69120 Heidelberg) and that we do not accept applications submitted via email. We apologize for any inconvenience this may cause.