Position: Scientist / Postdoctoral Researcher in Translational Genomics in part-time (50%)

Department: DKTK Essen - Translational Genomics in Solid Tumors

Code number: 2020-0273

The German Cancer Research Center is the largest biomedical research institution in Germany. With more than 3,000 employees, we operate an extensive scientific program in the field of cancer research.

Together with university partners at seven renowned partner sites, we have established the German Cancer Consortium (DKTK).
For the partner site of DKTK Essen the German Cancer Research Center is seeking a research scientist / postdoc. The position is located at the University Hospital Essen in the laboratory of Translational Genomics in Solid Tumors, led by Dr. Samuel Peña-Llopis.

We invite applications for highly enthusiastic and talented postdoctoral candidates to work in the field of translational oncology to identify new pathways in tumor progression that could be exploited therapeutically.


Job description:

Our group focuses on renal cell carcinoma and uveal melanoma, two tumor types with high frequency of mutations in the epigenetic modifier and tumor suppressor gene BAP1. We are interested in further understanding the higher tumor aggressiveness and patient metastasis caused by BAP1 mutations to ultimately develop novel therapies. To tackle this challenge, a combination of bioinformatics and state-of-the-art technologies, such as molecular genomics, CRISPR/Cas9, patient-derived organoids and mouse models of metastasis will be used.

Your tasks include:

  • Project management, implementation, analysis and publication of results in the area of ​​translational cancer genomics and pathway discovery
  • Supervision of students of the research group
  • Participation in collaborations in a multidisciplinary setting


  • Applicants must hold a PhD and M.Sc. degree in biochemistry, biomedicine, biotechnology, molecular biology, or a related discipline
  • Extended expertise and experiences with basic and advanced cellular and molecular biology techniques are essential; expertise in miRNAs, big data analyses and bioinformatics are desirable but not required
  • High motivation, strong commitment, reliability, attention to detail and capacity to assume independent responsibility to her/his projects
  • Excellent written and oral command of English is essential
  • Strong communication and teamwork skills are required
  • An accredited animal handling course, such as Felasa B, is a great advantage, but not a requirement
  • Enthusiasm for working in an international and multidisciplinary team and passion for making a difference through cancer research


We offer:

  • Interesting, versatile workplace
  • International, attractive working environment
  • Campus with modern state-of-the-art infrastructure
  • Salary according to TV-L including social benefits
  • Possibility to work part-time
  • Flexible working hours
  • Comprehensive further training program
  • Access to the DKFZ  International Postdoc Program

Earliest possible start date: as soon as possible

Duration: The position is limited to 1 year.

The position can in principle be part-time.

Application deadline: 03.12.2020


Dr. Samuel Pena-Llopis
Phone +49(0)201/723-6388

Please note that we do not accept applications submitted via email.

The DKFZ is committed to increase the proportion of women in all areas and positions in which women are underrepresented. Qualified female applicants are therefore particularly encouraged to apply.

Among candidates of equal aptitude and qualifications, a person with disabilities will be given preference.

To apply for a position please use our online application portal (www.dkfz.de/jobs).

We ask for your understanding that we cannot return application documents that are sent to us by post (Deutsches Krebsforschungszentrum, Personalabteilung, Im Neuenheimer Feld 280, 69120 Heidelberg) and that we do not accept applications submitted via email. We apologize for any inconvenience this may cause.