Position: Postdoctoral Fellow in Molecular Biology / Cancer Genetics / RNA Biology
Department: DKTK Freiburg, Division of Cancer Research, Department of Thoracic Surgery
Code number: 2019-0018
The German Cancer Research Center is the largest biomedical research institution in Germany. With approximately 3,000 employees, we operate an extensive scientific program in the field of cancer research.
Together with university partners at seven renowned partner sites, we have established the German Cancer Consortium (DKTK).
For the partner site of DKTK Freiburg the German Cancer Research Center is seeking a postdoctoral fellow.
Our research division explores the molecular mechanisms underlying carcinogenesis with a special emphasis on the role of non-coding RNAs and RNA-Protein complexes (Cell 2007, Nat Cell Biol 2009, Genome Res 2011, Cancer Res 2013, Nat Commun 2014, Nucleic Acids Res 2017, Mol Cell - in revision) as well as novel types of mutations (EMBO Mol Med 2016, Nat Genet - in revision, Nat Commun - in revision). The method spectrum in our lab ranges from innovative techniques from molecular and cell biology like diverse CRISPR techniques (Nucleic Acids Res 2017) or RNA-protein complex identification (Nature 2015) to applications in bioinformatics and biochemistry. Our lab in Freiburg is newly equipped with state-of-the-art instrumentation.
We are seeking a highly motivated postdoctoral fellow with significant and published experience in the area of molecular biology and cancer research, ideally in cancer genetics. The core project of the postdoctoral fellow will be the functional characterization of non-canonical genetic alterations in cancer. Research questions will include their impact on mRNA and protein expression and their mechanistic impact at the molecular level. An innovative medium-throughput screen using CRISPR site-directed mutagenesis shall unravel their impact in the endogenous setting in haploid human cells. Comprehensive resources as well as established protocols to build on are available. Jointly with the division head, new projects within the focus area of the lab can also be developed and supported to allow the growth into scientific maturity and independence.
You are a highly motivated postdoctoral fellow with a PhD / Dr. rer. nat. in a life science field and are eager to pursue and lead research projects on the molecular biology of lung cancer or tumor genetics with creativity, ambition, independence and team spirit. You have published experience in techniques of cellular and molecular biology or cancer research. Practical knowledge of bioinformatics would be welcome. You work efficiently, goal-oriented and accurate, have a deep interest in research and are proficient in English.
- Interesting, versatile workplace
- International, attractive working environment
- Campus with modern state-of-the-art infrastructure
- Salary according to TV-L including social benefits
- Possibility to work part-time
- Flexible working hours
- Comprehensive further training program
- Access to the DKFZ International Postdoc Program
Earliest Possible Start Date: as soon as possible
Duration: The position is limited until 31.12.2020.
Application Deadline: 28.02.2019
Prof. Dr. Sven Diederichs
Please note that we do not accept applications submitted via email.