Position: PhD Student in Molecular Cell Biology
Department: Cell Cycle Control and Carcinogenesis
Code number: 2021-0051
The German Cancer Research Center is the largest biomedical research institution in Germany. With more than 3,000 employees, we operate an extensive scientific program in the field of cancer research.
The PhD project is focused on the interplay between the formation of focal adhesions (FA) and the organization of the mitotic spindle apparatus in metastatic breast cancer. Mitotic spindle orientation abnormalities and loss of cell adhesion have been proposed to facilitate cancer invasion and metastasis, yet the molecular mechanisms underlying these processes are largely unknown. Different state-of-the-art techniques will be applied (i.e. live-cell imaging, cellular invasion assays, cell migration assays, proteomic screens). (Zhu et al., J. Cell Biol. 2013, 200: 773–787; Kschonsak and Hoffmann, J Cell Sci 2018, doi:10.1242/jcs.214544).
We offer working in an enthusiastic international environment, detailed initial skill adaptation training regarding methods, excellent guidance, regular lab meetings and literature seminars, lab retreats, possibility to attend national and international conferences and membership in the Helmholtz International Graduate School.
Applicants should hold a diploma / master's degree in biology / life sciences with outstanding grades, have a strong background in biochemistry and molecular cell biology and excellent laboratory and analytical skills.
Full applications should include curriculum vitae, a letter of motivation, transcripts of records of both bachelor and master studies and the names and contact details of two referees.
- Interesting, versatile workplace
- International, attractive working environment
- Campus with modern state-of-the-art infrastructure
- Access to international research networks
- Doctoral student payment including social benefits
- Flexible working hours
- Comprehensive training and mentoring program through the Helmholtz International Graduate School
Earliest Possible Start Date: 03.05.2021
Duration: The position is limited to 3 years with the possibility of prolongation.
Application Deadline: 17.03.2021
Prof. Dr. Ingrid Hoffmann
Phone +49 (0)6221/42-4908
Please note that we do not accept applications submitted via email.