Position: PhD Student in Molecular Cell Biology

Department: Cell Cycle Control and Carcinogenesis

Code number: 2021-0051

The German Cancer Research Center is the largest biomedical research institution in Germany. With more than 3,000 employees, we operate an extensive scientific program in the field of cancer research.

Job description:

The PhD project is focused on the interplay between the formation of focal adhesions (FA) and the organization of the mitotic spindle apparatus in metastatic breast cancer. Mitotic spindle orientation abnormalities and loss of cell adhesion have been proposed to facilitate cancer invasion and metastasis, yet the molecular mechanisms underlying these processes are largely unknown. Different state-of-the-art techniques will be applied (i.e. live-cell imaging, cellular invasion assays, cell migration assays, proteomic screens). (Zhu et al., J. Cell Biol. 2013, 200: 773–787; Kschonsak and Hoffmann, J Cell Sci 2018, doi:10.1242/jcs.214544).

We offer working in an enthusiastic international environment, detailed initial skill adaptation training regarding methods, excellent guidance, regular lab meetings and literature seminars, lab retreats, possibility to attend national and international conferences and membership in the Helmholtz International Graduate School.



Applicants should hold a diploma / master's degree in biology / life sciences with outstanding grades, have a strong background in biochemistry and molecular cell biology and excellent laboratory and analytical skills.

Full applications should include curriculum vitae, a letter of motivation, transcripts of records of both bachelor and master studies and the names and contact details of two referees.

We offer:

  • Interesting, versatile workplace
  • International, attractive working environment
  • Campus with modern state-of-the-art infrastructure
  • Access to international research networks
  • Doctoral student payment including social benefits
  • Flexible working hours
  • Comprehensive training and mentoring program through the Helmholtz International Graduate School

Earliest Possible Start Date: 03.05.2021

Duration: The position is limited to 3 years with the possibility of prolongation.

Application Deadline: 17.03.2021


Prof. Dr. Ingrid Hoffmann
Phone +49 (0)6221/42-4908

Please note that we do not accept applications submitted via email.

The DKFZ is committed to increase the proportion of women in all areas and positions in which women are underrepresented. Qualified female applicants are therefore particularly encouraged to apply.

Among candidates of equal aptitude and qualifications, a person with disabilities will be given preference. 

To apply for a position please use our online application portal (https://www.dkfz.de/en/stellenangebote/index.php).

We ask for your understanding that we cannot return application documents that are sent to us by post (Deutsches Krebsforschungszentrum, Personalabteilung, Im Neuenheimer Feld 280, 69120 Heidelberg) and that we do not accept applications submitted via email. We apologize for any inconvenience this may cause.