Job description:

The project aims to dissect potentially druggable drivers of immune escape by oncogenic signaling pathways in liver cancer, using translational approaches and preclinical cancer models. Different state-of-the-art techniques will be applied, including novel, organoid-based transplantation cancer models, genetic perturbation of cancer and stromal cells and single-cell sequencing. The project will additionally involve the analysis and integration of multiple types of data to address questions in translational cancer biology.

We offer work in an international, motivating environment, collaborative possibilities in both basic and medical science, and close interactions with clinical partners that provide unique opportunities for a scientist with interdisciplinary interests.

Requirements:

The ideal candidate should hold a PhD degree in biology/ life sciences with an excellent background in biochemistry, cell or molecular biology. We look for a highly motivated and curious researcher with a strong interest in cancer biology and cell signaling. Additionally, the candidate should have experience in cell culture and molecular biology techniques. Experience in animal models of cancer and/ or computational skills would be of advantage. Furthermore, we expect passion for independent thinking, fluency in written and spoken English and a collaborative nature.

Applications should consist of a single pdf file including a curriculum vitae, a cover letter stating research and career interests, letter of recommendation and contact details of two referees.