Position: PhD Student in Preclinical Neurooncology

Department: Pediatric Neurooncology

Code number: 2021-0097

The German Cancer Research Center is the largest biomedical research institution in Germany. With more than 3,000 employees, we operate an extensive scientific program in the field of cancer research.

Job description:

We are seeking exceptional candidates to fill a PhD position in the field of pediatric neurooncology. The project aims to identify synergistic treatment combinations against pediatric high-grade glioma. Initially, within a comprehensive screening approach, a library of clinically relevant small molecule inhibitors will be combined with modern radiation modalities to analyze the impact on growth and survival in a large collection of primary tumor cell cultures. Subsequently, promising combinations will be validated through additional in vitro and in vivo pre-clinical testing. The project involves a diverse range of tasks including in vitro studies in the S1 and S2 laboratory as well as work with mice, while utilizing state-of-the-art methodologies (novel therapeutics, CRISPR, high-throughput sequencing, autochthonous and transplantation-based animal models). Additionally, the PhD student will share common laboratory tasks and administrative duties with colleagues as part of a supportive team environment.



  • Master’s degree in biology or similar field of study
  • Initiative towards planning own and common tasks
  • Experience with basic molecular biology techniques (cloning, DNA / protein extraction, Western Blot, cell culture etc.)
  • Curiosity towards expanding scientific knowledge and new opportunities
  • Fluent English
  • Collegiality and ability to work well in a team
  • Engagement and motivation for pursuing a research project from planning through to analysis and presentation of results
  • Experience with preclinical models in vitro and/or in vivo is strongly preferred

We offer:

  • Interesting, versatile workplace
  • International, attractive working environment
  • Campus with modern state-of-the-art infrastructure
  • Access to international research networks
  • Doctoral student payment including social benefits
  • Flexible working hours
  • Comprehensive training and mentoring program through the Helmholtz International Graduate School

Earliest Possible Start Date: as soon as possible

Duration: The position is limited to 3 years with the possibility of prolongation.

Application Deadline: 23.04.2021


Dr. Marc Zuckermann
Phone +49 6221 42 4637

Please note that we do not accept applications submitted via email.

The DKFZ is committed to increase the proportion of women in all areas and positions in which women are underrepresented. Qualified female applicants are therefore particularly encouraged to apply.

Among candidates of equal aptitude and qualifications, a person with disabilities will be given preference. 

To apply for a position please use our online application portal (https://www.dkfz.de/en/stellenangebote/index.php).

We ask for your understanding that we cannot return application documents that are sent to us by post (Deutsches Krebsforschungszentrum, Personalabteilung, Im Neuenheimer Feld 280, 69120 Heidelberg) and that we do not accept applications submitted via email. We apologize for any inconvenience this may cause.