Position: Postdoctoral Scientist in Cancer Metabolism
Department: Tumour Metabolism and Microenvironment
Code number: 2021-0310
The German Cancer Research Center is the largest biomedical research institution in Germany. With more than 3,000 employees, we operate an extensive scientific program in the field of cancer research.
Altered metabolism is a hallmark of cancer and metabolic reprogramming in cancer supports the synthesis of macromolecules for cell growth and proliferation. Metabolic reprogramming can also be a driver of transformation and generates selective vulnerabilities that can be exploited for cancer therapy.
The Division of Tumor Metabolism and Microenvironment aims to unravel the cross-talk between oncogenic signaling networks and metabolic processes in cancer cells. We are also interested in the mechanisms by which altered metabolism associated with metabolic diseases drive cancer initiation and progression. We apply state-of-the-art methodologies, including advanced tissue culture, RNAi and CRISPR/Cas technology, transcriptomics and proteomics techniques as well as targeted metabolomics, metabolic flux analysis and stable isotope tracing.
As successful candidate you will use the above mentioned methods as part of an interdisciplinary research project elucidating the deregulation of lipid metabolism in non-alcoholic fatty liver disease and hepatocellular carcinoma.
We are looking for a highly motivated scientist holding a PhD in chemistry, biochemistry or molecular biology, with practical experience in cancer biology. Good knowledge of cancer biology and experience in cell culture, biochemical assays, metabolism and cell signaling is desired. Candidates with experience in functional genomics, metabolomics or lipidomics will be preferred. Experience in the analysis of large datasets (e.g. using R) is of value. The project is part of an interdisciplinary consortium and excellent communications skills in English are essential. We are offering an international and collaborative working environment with access to high-end instrumentation.
Full applications including a cover letter, curriculum vitae, a summary of the PhD thesis, certificates and names of three references should be submitted via our online application portal (https://www.dkfz.de/de/stellenangebote/index.php).
- Interesting, versatile workplace
- International, attractive working environment
- Campus with modern state-of-the-art infrastructure
- Salary according to TV-L including social benefits
- Possibility to work part-time
- Flexible working hours
- Comprehensive further training program
- Access to the DKFZ International Postdoc Program
Earliest possible start date: as soon as possible
Duration: The position is initially limited to 2 years with the possibility of prolongation.
The position can in principle be part-time.
Application deadline: 09.11.2021
Prof. Dr. Almut Schulze
Phone +49 6221 42-3423
Please note that we do not accept applications submitted via email.