Position: Technical Assistant for Personalized Immunotherapy

Department: Personalized Immunotherapy

Code number: 2024-0154

The German Cancer Research Center is the largest biomedical research institution in Germany. With more than 3,000 employees, we operate an extensive scientific program in the field of cancer research.

The Helmholtz Institute HI-TRON is a collaboration of the German Cancer Research Center (DKFZ) with the Research Institute for Translational Oncology at the University Medical Center of the Johannes Gutenberg University Mainz (TRON gGmbH), the University Medical Center Mainz and the Johannes Gutenberg University Mainz. The goal of the partnership is to develop effective immunotherapies and to identify novel biomarkers for assessing the effectiveness of treatment.

The Türeci Lab at HI-TRON Mainz is seeking a proficient and motivated technical assistant to join our dynamic team. We are searching for someone with a solid background in onco-immunology and a drive to innovate new platforms. The successful candidate will play a pivotal role in managing laboratory operations while contributing significantly to our research and development efforts.


Job description:

    • Oversee day-to-day laboratory operations and assist fellow lab members with practical tasks, including:
      • Cell culture: cultivation of human and mouse cell lines and primary immune cells
      • Molecular biology and cellular manipulation: conducting DNA and RNA isolation, cDNA synthesis, PCR, cloning, transfection, and transduction
      • Conduct western blotting, ELISA, and various staining techniques for immunofluorescence, immunohistochemistry, and flow cytometry
      • Engage in in-vivo work: monitor animals and support other lab members with animal experiments (e.g., inoculations, dissections, tissue sampling, and processing)
    • Support the development, implementation, and optimization of new processes and methodologies
    • Assume responsibility for logistical and administrative duties in the lab, such as equipment maintenance, supply procurement, and documentation


    • Education as a technical assistant (e.g. BTA) or biology laboratory technician
    • Proficiency in standard molecular and cell biology techniques
    • Experience in cultivating and engineering primary human cells and mammalian cells
    • Familiarity with immune profiling using flow cytometry and/or microscopy techniques
    • Desirable prior exposure to animal experimentation in immuno-oncology
    • Experience in laboratory management
    • Proficiency in German and English, both written and verbal
    • Highly organized and structured approach to work, with a problem-solving orientation
    • Thorough documentation of work activities
    • Motivated and eager to acquire new skills
    • Strong teamwork ethic, positive attitude, and creativity
    • Willingness to supervise and support student projects

    We offer:

    • Excellent framework conditions: state-of-the-art equipment and opportunities for international networking at the highest level
    • Compensation according to TV-L incl. occupational pension plan and capital-forming payments
    • 30 days of vacation per year
    • Possibility of part-time work
    • Family-friendly working environment, e.g. parent-child room and advisory services
    • Sustainable travel to work: subsidized Germany job ticket
    • Unleash your full potential: targeted offers for your personal development to further develop your talents
    • Our Corporate Health Management Program offers a holistic approach to your well-being

    Important notice:

    The DKFZ is subject to the regulations of the Infection Protection Act (IfSG). As a consequence, only persons who present proof of immunity against measles may work at the DKFZ.

    Earliest Possible Start Date: as soon as possible

    Duration: The position is initially limited to 2 years with the possibility of prolongation.

    Application Deadline: 05.06.2024


    Dr. Ibrahim Murathan Sektioglu
    Phone +49 (0)6131/179816

    Please note that we do not accept applications submitted via email.

    The DKFZ is committed to increase the proportion of women in all areas and positions in which women are underrepresented. Qualified female applicants are therefore particularly encouraged to apply.

    Among candidates of equal aptitude and qualifications, a person with disabilities will be given preference.

    To apply for a position please use our online application portal (https://www.dkfz.de/en/stellenangebote/index.php).

    We ask for your understanding that we cannot return application documents that are sent to us by post (Deutsches Krebsforschungszentrum, Personalabteilung, Im Neuenheimer Feld 280, 69120 Heidelberg) and that we do not accept applications submitted via email. We apologize for any inconvenience this may cause.